Right now it all depends on where you are
In Sydney theres a lot of Big Brother (cause people spent lots of money to get the necessities for the deck and feel they have to play it <cough> Ray <cough>)
Common Enemy is/will also be big, as the Sydney Meta-game usually tends towards the latest winners of the latest big event. Heaven forbid Chris Foggin wins a PC with his Fearsome Five deck as you wont be able to get Mammoths anywhere (but you could get Psimons from Tony)
Sentinels is also around, although I don't think for long, as it is cheap but dies miserably to flame trap
the more popular decks also have come from DC, even though they may not be the strongest, more people have the cards from this set as it is the one more people have drafted with. If only poeple got into this game when it first came out!
When it comes down to it, if your deck can't beat Big Brother, Common Enemy or a beatdown strategy like TNB or Teen Titans, I wouldn't bother running it. If you can beat two of these type of decks then I say go for it and hope you don't hit your bad match-ups =) gl
Scott